Development of interactive e-module based on video and augmented reality for earthquake technology course

The application of augmented reality and video in instructional media is highly suitable for courses in the field of civil engineering, one of which is the Earthquake Technology course. This research employs the Research and Development (R&D) method using the ADDIE model in developing the e-module. The result of this research is a dedicated e-module specifically designed for the Earthquake Technology course. The e-module has been assessed by media experts, subject matter experts, and students as part of the evaluation process. The average scores from the two media experts are 93.33 and 91.33 for graphic feasibility, and 96.67 and 93.33 for language feasibility. As for the two subject matter experts, the average scores for content feasibility are 87.06 and 87.06, for presentation feasibility are 87.50 and 90.00, and for contextual feasibility are 90.00 and 90.00. Meanwhile, the average score from the students during the limited classroom trial is 89.06. The results of this research indicate that the development of the Earthquake Technology e-module using the ADDIE method has resulted in an e-module of "very good" category in terms of media and "good" category in terms of content. The assessment results from students also indicate that the Earthquake Technology e-module falls into the "good" category. So, it can be concluded that the Earthquake Technology e-module based on video and augmented reality can be totally applied in the learning process of Earthquake Technology course at The Civil Engineering Education Program, Universitas Negeri Semarang

Microrna-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice

Induction of endogenous regenerative capacity has emerged as one promising approach to repair damaged hearts following myocardial infarction (MI). Re-expression of factors that are exclusively expressed during embryonic development may reactivate the ability of adult cardiomyocytes to regenerate. Here, we identified miR-411 as a potent inducer of cardiomyocyte proliferation. Overexpression of miR-411 in the heart significantly increased cardiomyocyte proliferation and survival in a model MI. We found that miR-411 enhances the activity of YAP, the main downstream effector of the Hippo pathway, in cardiomyocytes. In conclusion, miR-411 induces cardiomyocyte regeneration and improves cardiac function post-MI likely by modulating the Hippo/YAP pathway